Griffin od wielu lat mieszka w Santa Barbara w Kalifornii, gdzie był wykładowcą w latach 1973-2004. Obecnie jest w zarządzie Center for Process Studies, które promuje studia nad teologią procesu, bazującą na filozofii procesu. Badania w tym kierunku zapoczątkowali Alfred North Whitehead i Charlesa Hartshorne'a.
Publikacje
W dziedzinie filozofii i teologii A process Christology, Westminster Press, 1973, Process Theology: An Introductory Exposition, z Johnem B. Cobbem, Philadelphia: Westminster Press, 1976, John Cobb's Theology in Process, Westminster John Knox Press, 1977, Process and Reality, Free Press; 2 wydanie, 1979, Physics and the Ultimate Significance of Time: Bohm, Prigogine and Process Philosophy, State University of New York Press, 1986, The Reenchantment of Science: Postmodern Proposals (Suny Series in Constructive Postmodern Thought), State Univ of New York Press, 1988, Spirituality and Society: Postmodern Visions (Suny Series in Constructive Postmodern Thought), State University of New York Press, 1988, Varieties of Postmodern Theology (Suny Series in Constructive Postmodern Thought), State University of New York Press, 1989, God and Religion in the Postmodern World: Essays in Postmodern Theology (Constructive Postmodern Thought), State University of New York Press, 1989, Archetypal