Le Warren Alpert Foundation Prize (prix de la Fondation Warren Alpert) est un prix scientifique décerné chaque année à des scientifiques dont les réalisations ont conduit à la prévention, à la guérison ou au traitement de maladies ou de troubles humains, et/ou dont la recherche constitue une découverte scientifique fondamentale qui est très prometteuse de changer à terme notre compréhension ou la capacité de traiter la maladie.

Histoire Le prix est créé en 1987 par le philanthrope et homme d'affaires Warren Alpert et la Fondation Warren Alpert.

Le prix Warren Alpert est décerné au niveau international et depuis sa création, dix lauréats ont également remporté un prix Nobel.

Le prix est administré de concert avec la Harvard Medical School à Boston, au Massachusetts, et la Warren Alpert Foundation, située à Providence, à Rhode Island. Un symposium annuel est organisé à la Harvard Medical School chaque automne où les récipiendaires présentent leurs travaux. Le prix comprend , une citation et une plaque.

Lauréats du prix Année Lauréats Citation Nationalité2020 Daniel Drucker, Joel Habener et Jens Juul Holst Pour l'identification des peptides de type glucagon et être leader dans ce domaine avec des études poussées des cellules aux humains, aboutissant au développement de ces peptides en tant qu'agents thérapeutiques pour le traitement du diabète et du syndrome de l'intestin court. 2019 Ed Boyden, Karl Deisseroth, Peter Hegemann et Gero Miesenböck For pioneering work in the field of optogenetics, a revolutionary technique that uses light and genetic modification to control the activity of cells in the brain. 2018 Francis Collins, Paul Negulescu, Bonnie Ramsey, Lap-Chee Tsui, Michael Welsh For identifying faulty gene behind devastating disease, development of precision-targeted therapies. 2017Arlene Sharpe, Harvard Medical School, Gordon Freeman, Dana Farber Cancer Institute, Lieping Chen, Yale University, James P. Allison, University of Texas M.D. Anderson Cancer Center, Tasuku Honjo, Kyoto University For their collective contributions to the pre-clinical foundation and development of immune checkpoint blockade, a novel form of cancer therapy that has transformed the landscape of cancer treatment. 2016Rodolphe Barrangou, North Carolina State University, Philippe Horvath, DuPont, Jennifer Doudna, University of California, Berkeley, Emmanuelle Charpentier, Max Planck Institute for Infection Biology et Umeå University, Virginijus Šikšnys, Vilnius University Institute of Biotechnology For their remarkable contributions to the understanding of the CRISPR bacterial defense system and the revolutionary discovery that it can be adapted for genome editing 2015Ruth Sonntag Nussenzweig et Victor Nussenzweig, NYU Langone Medical Center, Tu Youyou of the China Academy of Chinese Medical Sciences, Beijing For their pioneering discoveries in chemistry and parasitology, and their personal commitment to translating these discoveries into effective chemotherapeutic and vaccine-based approaches to controlling malaria 2014 Oleh Hornykiewicz, Medical University of Vienna, Roger A. Nicoll, University of California, San Francisco, Solomon H. Snyder, Johns Hopkins School of Medicine For seminal contributions to our understanding of neurotransmission and neurodegeneration 2013 David Botstein, Princeton University, Ronald W. Davis, Stanford University School of Medicine et David Hogness, Stanford University School of Medicine For their seminal contributions to the concepts and methods of creating a genetic map in the human, and of positional cloning, leading to the identification of thousands of human disease genes and ushering in the era of human genetics 2012 Julian Adams, Infinity Pharmaceuticals, Kenneth C. Anderson, Dana-Farber Cancer Institute, Alfred L. Goldberg, Harvard Medical School et Paul G. Richardson, Dana-Farber Cancer Institute For the discovery, preclinical and clinical development of bortezomib to FDA approval and front line therapy for the treatment of patients with multiple myeloma 2011 Alain Carpentier, Hôpital Européen Georges-Pompidou et Robert Langer, Massachusetts Institute of Technology For their application of bioengineering principles to fundamental improvements in human health 2009-2010 Howard Green, Harvard Medical School For development of methodologies for the expansion and differentiation of human keratinocyte stem cells for permanent skin restoration in victims of extensive burns 2008 Lloyd Aiello, Joslin Diabetes Center For the discovery, characterization and implementation of laser panretinal photocoagulation, which is used to treat proliferative diabetic retinopathy 2007Harald zur Hausen et Lutz Gissmann, German Cancer Research Center For work leading to the development of a vaccine against human papillomavirus 2006Dennis Slamon, UCLA ; Robert Weinberg, MIT ; Michael Shepard, Receptor BioLogix, Inc et Axel Ullrich, Center for Molecular Medicine, For their work in identifying HER-2/neu as an oncogene and development of the anti-HER-2/neu monoclonal antibody Herceptin for breast cancer therapy 2005M. Judah Folkman, Harvard Medical School et Boston Children's Hospital For discovering tumor angiogenesis, and for pioneering work in the development of antiangiogenic therapies for cancer 2004Susan Band Horwitz, Albert Einstein College of Medicine For her seminal contributions to the understanding of how the antitumor agent Taxol kills cancer cells. 2003Sidney Pestka, University of Medicine and Dentistry of New Jersey Robert Wood Johnson Medical School, David Goeddel, Tularik, Inc. et Charles Weissmann, Imperial College School of Medicine, London For purification and characterization of interferon alpha; cloning of the human interferon alpha gene and mass production of recombinant interferon alpha for cancer treatment and treatment of hepatitis C 2002Alfred Sommer, Johns Hopkins University Bloomberg School of Public Health For epidemiologic insight into the effects of Vitamin A deficiency, and the resulting reduction in childhood mortality worldwide 2001Eugene Braunwald, Harvard Medical School et Barry Coller, Rockefeller University School of Medicine. For work in cardiac physiology and pathophysiology, leading to the use of monoclonal antibodies to platelet surface antigens in antithrombotic therapy 2000David Baltimore, California Institute of Technology, Brian Druker, Oregon Health Sciences University, Nicholas Lydon, Amgen, Inc., Alex Matter, Novartis Pharma AG et Owen Witte, University of California, Los Angeles. For Development of Abl kinase inhibitors for use in the treatment of chronic myelogenous leukemia 1999Michael S. Brown et Joseph L. Goldstein, University of Texas Southwestern Medical School, Akira Endo (biochemist), Tokyo Noko University For Development of HMG CoA reductase inhibitors 1998K. Frank Austen, Harvard Medical School For elucidating the role of leukotrienes in asthma 1997Robert C. Gallo, University of Maryland School of Medicine et Luc Montagnier, Queens College, New York For isolation of the Human Immunodeficiency Virus 1996Leo Sachs, Weizmann Institute of Science et Donald Metcalf, University of Melbourne For discovery of blood cell growth factors 1995John A. Clements, University of California, San Francisco For discovery of lung surfactant, and development of synthetic lung surfactant therapy for Infant Respiratory Distress Syndrome 1994J.R. Warren, Royal Perth Hospital, and Barry J. Marshall, University of Virginia For linking gastric ulcers to the H. pylori bacterium 1993Stuart H. Orkin, Harvard Medical School. For genetic and molecular mechanisms of Βeta-Thalassemia and other blood disorders 1992 Roscoe O. Brady, National Institutes of Health For treatment for Gaucher’s Disease 1991 David W. Cushman et Miguel A. Ondetti, Bristol Myers-Squibb For ACE inhibitor therapy for hypertension and heart failure 1990 Aucun prix décerné.1989 Yuet Wai Kan, University of California, San Francisco For prenatal genetic screening for blood diseases 1988 Louis Kunkel, Harvard Medical School For discovery of the gene associated with a major form of muscular dystrophy 1987 Kenneth Murray (biologiste), University of Edinburgh For development of a vaccine against Hepatitis B

Voir également Liste des prix en sciences biomédicales

Notes et références

Liens externes

Faculté de médecine de Harvard Prix de la Fondation Warren Alpert

Catégorie:Prix scientifique aux États-Unis Catégorie:Université Harvard Catégorie:Distinction en médecine Catégorie:Distinction fondée en 1987