Laodika II. (starogrško , Laodíkē) je bila soproga Selevka II. Kalinika, vladarja Selevkidskega cesarstva.Alten, Elif (2017). "Revolt of Achaeus Against Antiochus III the Great and the Siege of Sardis, Based on Classical Textual, Epigraphic and Numismatic Evidence". In Laflı, Ergün; Kan Şahin, Gülseren (ur.). Archaeology and History of Lydia from the Early Lydian Period to Late Antiquity (8th century B.C.-6th century A.D.). An international Symposium May 17-18, 2017 / Izmir, Turkey. Abstracts Booklet. Colloquia Anatolica et Aegaea, Acta Congressus Communis Omnium Gentium Smyrnae. IV. The Research Center for the Archaeology of Western Anatolia – EKVAM. str. 27. OCLC 6848755244.
Po izrecni Polibijevi izjavi je bila sestra Andromaha, anatolskega plemiča grško/makedonskega in perzijskega porekla.Bunbury, Edward Herbert (1872). "Laodice". V Smith, William (ur.). A Dictionary of Greek and Roman Biography and Mythology. II. John Murray. str. 718. OCLC 9176630. V zakonu s Selevkom II. je rodila selevkidska vladarja Selevka III. Kerauna in Antioha III. Velikega.Bunbury 1872, str. 719.
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